Prevalence of ESBL enzymes in Klebsiella pneumoniae isolated from Tohid Hospital sanandaj,iran

نهمين كنگره بين المللي آزمايشگاه و بالين و دومين كنگره ملي علوم پايه پزشكي و توليد دانش بنيان

3 الي 6 اسفند 1395، تهران - ايران

Presentation Type: Poster
Abstract: Background and Aim : Klebsiella pneumoniae (K. pneumoniae) is a Gram negative and members of the Enterobacteriaceae family, which is known as one of the most common causes of nosocomial infections. In treatment of K. pneumoniae, Cephalosporins is the first line treatment but now the most common resistance to cephalosporins has been reported. In gram-negative bacteria such as K. pneumoniae producing ESBL enzymes are the most common cause of resistance to cephalosporins. The aim of this study was detection of ESBL producing enzymes in K. pneumoniae isolated from Tohid Hospital Sanandaj,Iran.
Methods : In this study, 26 K. pneumoniae from Tohid Hospital in Sanandaj were collected in sixmonth period in 2015-2016, then were identified using standard biochemical tests. Antibiotic sensitivity testing done by disk diffusion method and generates ESBLS were determined by using phenotypic tests such as combine disk diffusion according to CLSI.
Results : out of 26 K. pneumoniae 17 isolates producing ESBLs that identified by using phenotypic test.
Conclusion : The results of this study and previous studies suggest the prevalence of ESBLproducing K. pneumoniae is high .Recently, the ESBL-producing isolates of the main problems in the treatment of nosocomial infections.