Fertility issues in young breast cancer survivors: A review
29 الي 30 اردیبهشت 1395، شيراز - ايران
Presentation Type: Speech
Abstract: Background: Breast cancer is the most common cancer in women. Treatment have acute and chronic long-term side effects can cause significant symptoms in woman’ s reproductive issues. The purpose of this study to review of the treatment and the related factors to infertility in young adults with breast cancer.
Methods: The researchers primarily searched in public record databases on the Internet, including Google Scholar and more specifically in Persian databases SID, Magiran, Irandoc and then Web Of Science, Science Direct, PubMeb and in Medical Journals and Elsevier using the Subject Heading (MeSH) and Text Word method, the relevant papers were selected from the years 2000-2016. At first, 50 studies were included in the Abstract Screening phase. In the following, 10 papers were excluded in Full Text Screening phase. Finally, the data of 40 papers were extracted.
Results: Findings show that one of the major concerns associated with future fertility. This concern caused mental distress that affect their self-esteem and self-concept. This results in a 4 classes and two under-class organized. First-class treatment and its impact on people encompass: treatment such as surgery, chemotherapy, radiotherapy, endocrine therapy have negative impact on sexual function that is impaired fertility. The second chasses includes cancer’ s physical issues and treatment of infertility related on. 5 studies include data related on treatments side effect leading amenorrhea and early menopause that pointed out Shortness opportunities for patients to be conceived. 20studiesrelated to chemotherapy-induced amenorrheanoted that this type of treatment caused anxiety due to loss of fertility and reducing ovarian reserves. Fertility preservation is the third class strategies. Using strategies such as embryo cryopreservation, oocyte cryopreservation, and temporary support ovarian hormones in the young child with breast cancer are helpful. At Fourth classes: the psychological aspect refers fertility. Most of the anxiety symptoms related on infertility. most of patient’ s concern is related on infertility treatment. Given that pregnancy is not recommended during treatment and after treatment which have not role in probability of relapses. But there is concern in patients, and evidence shows that patients tend to use less effective treatments due to fertility complications. Concerns about strategy of maintaining a pregnancy, fear of negative impact of pregnancy, safety fertility methods and negative impact of ovarian stimulation are reported.
Conclusion: Further efforts to improve reproductive issues in patients need to apply health care providers and medical team familiar with the guidelines and evidence-based information and knowledgeable consultants about fertility issues before treatment (Fertility preservation techniques, possible side effects success rate, costs) Which can play an important role in raising awareness of the disease and reducing their stress and this can be helpful in counseling patients