Presentation Type: Poster
Abstract: Background: The breast cancer is the most prevalence cancer among the women and the most important element of death due to cancer in women around the world. The breast cancer has been dedicated seventeen percentages of total women's cancers and also is in the first rate. This study has been implemented in order to survey frequency of axillary lymph node involvement in female patients with breast cancer.
Methods: The method of study is descriptive. The samples of study are of 168 female patients defected to breast cancer in hospitals, Shahid Beheshti of Babol and Shahid Rajaei of Tonekabon and Imam Sajjad of Ramsar from 1391 until the end of 1393. Criteria for admission have included the female patients infected to breast cancer and the exclusion criteria are not to report the LN in pathology sheet (NX), and uncomplicated documents of patients. The information were registered and collected as a checklist and statistically analyzed through SPSS 21 software.
Results: Axillary lymph node involvement was seen 117 cases (70.1%) among our patients. The patients' mean age was 49.64 ± 11.62 in year (22-81). The most prevalence age group was 40-49 (39.2%) that had the most lymph node involvement in all patients (24.0%) in this group. The average size of tumor was 3.39 cm, so most patients(98 cases, 58.7%) had a tumor size 2-5 cm (T2) but the most involvement has been related to T3 (>5cm) with 23 patients (100.0%). The most common tumor type and grade was invasive ductal carcinoma with156 patients (93.4%) and grade 2 with 87 patients (52.1%). Most lymph node involvement than total individuals infected to LN+ was been 111 patients (94.9%) in invasive ductal carcinoma and 85.1% in patients with degree 3 had the most lymph node involvement. The vessels invasion was 37 cases (22.2%) of 48 patients with vessels involvement had axillary lymph node involvement. Most tumors have plus receiver of estrogen and progesterone (97 cease, 63.8%).
Conclusion: There is a statistically significant relation between axillary lymph node involvement and tumor, size, grade, estrogen/progesterone receptor status, and type while there isn't any significant relation between axillary lymph node involvement age and ER PR status.