EVALUATING THE EXPRESSION OF MEXAB - OPRM EFFLUX PUMP GE NES IN RESISTANT CLINICAL ISOLATES OF PSEUDOMONAS AERUGINOSA USING QUANTITATIVE REAL - TIME PCR METHOD
23 till 25 August 2016، Tehran - Iran
Presentation Type: Speech
Background and Aim: Pseudomonas aeruginosa is a highly drug - resistant and opportunistic pathogen. The MexAB - OprM efflux pump contributes to the intristic resistance to various antimicrobial agents in Pseudomonas aeruginosa isolated from patients. The aim of this study was to evaluate the expression of MexAB - OprM efflux pump such as MexA, MexR and gyrA as housekeeping genes using Quantitative Real - Time PCR method in ATCC 27853 strain and resistant clinical isolates.