Background and Aim: Chlamydia trachomatis (CT) is one of the most common infection transmitted through sexual intercou rse. The purpose of this study was to investigate the role of CT infection and preterm delivery method by a meta - analysis.
Methods: The most available article published in literature database including PubMed, Science direct, Web of Science, Google Scholar, Biological abs, Iranmedex, and SID were investigated and 21 relevant articles, performed during 1998 - 2014 and then a random - effects model was used for data analysis. Heterogeneity of studies was evaluated by I2 index. The relationship between year of data collection, sample size, and CT infection with preterm delivery prevalence examined by meta - regression. Data were analyzed by R software and STATA [Ver 11.2].
Results: Among the 24 studies evaluated the prevalence of CT infection with preterm delivery was estimated 0.13% (CI 95%: 0.11 - 0.16). The prevalence of CT infection with preterm delivery based on study method including PCR 0.06 (CI 95%: 0.04 - 0.09), serology 0.23 (CI 95%: 0.10 - 0.35) and culture 0.17 (CI 95%: 0.10 - 0.24) was estimated. The prevalence of CT infection with preterm delivery based on study type including case - control 0.16 (CI 95%: 0.11 - 0.21), and cross - sectional 0.13 (CI 95%: 0.08 - 0.17) was estimated. the prevalence of CT infection with preterm delivery based type Continental including Europ e 0.13 (CI 95% : 0.09 - 0.18), Asia 0.08 (CI 95% : - 0.01 - 0.17), USA 0.15(CI 95% : 0.08 - 0.22) and Africa 0.29(CI 95% : 0.23 - 0.34) was estimated .
Conclusion: In regard to the results and studies performed on different populations, this meta - analysis showed no associated between preterm birth and CT