ENHANEMENT OF HIV - 1 PROTEIN VACCINATION USING CELL PENETRATING PEPTIDES
23 till 25 August 2016، Tehran - Iran
Presentation Type: Speech
Background and Aim: The HIV - 1 regulatory proteins tat and nef are attractive as vaccine components since they are the HIV - 1 critical proteins and AIDS disease progression . For vaccine development, different types of lipid - and polymer - based vectors such as liposomes, microparticles and nanoparticles have been used for protein delivery, but with relatively poor success. Recently, a group of short, highly basic peptides known as cell - penetrating peptides (CPPs) were used to carry polypeptides and proteins into cells.