A prospective study of etiologies of Hirsutism and screening for non classic congenital adrenal hyperplasia due to 21 Hydroxylase deficiency in 93 female adolescents

Acta Medica Iranica Journal

Volume 38 - Number 4

Article Type: ---- Unspecified ----

In this study 93 hirsute females (Ferryman and Gallway score>8) referred to institute of endocrinology and metabolism and office were assessed. Baseline testosterone (Tes), Dehydroepiandrosterane sulfate (DHEA-SO4). Follicular stimulating hormone (FSH), Luteinizing hormone (LH), Prolactin (PRL), Thyroid stimulating hormone (TSH), baseline 17 hydroxyprogesterone (17-OHP) and in some cases ACTH stimulation test for screening of non-classic congenital adrenal hyperplasia (NC-CAH) due to 21 hydroxylase deficiency was done. The ovaries were visualized by ultrasonography in 56 patients, of the 93 hirsute female, 5 had NC-CAH (5.4%), 46 patients diagnosed as having polycystic ovary syndrome (49.5%) and 42 cases diagnosed as having idiopathic hirsutism (45.1%).

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