Chemotherapy of lymphoma complicating immunoproliferative small intestinal disease (IPSID): The comparison of Doxorubicin (DOX)-based protocols with non-DOX regimens

Iranian Journal of Medical Sciences

Volume 17 - Number 3-4

Article Type: ---- Unspecified ----
Abstract:

The purpose of the present study is to compare the clinical results of different protocols in the treatment of IPSID-related lymphoma in Iran. 41 Iranian patients with IPSID-related lymphoma were studied retrospectively. 21 patients had received a dox-based protocol and 20 patients were treated with other regimens lacking dox. The following results were shown in this study: The survival rate is 71.4% in the dox group compared with 35% in the other (P<0.05 chi-square). The disease-free interval is 16.3 months in the dox group compared with 11.2 in the non-dox group (P<0.001 unpaired student T-test). The incidence of non-fatal complications in the 2 groups is slightly different but not statistically significant (0.25

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