The effects of Gum Olibanumin complementary medicine on the treatment of diabetic patients

Avicenna Journal of Phytomedicine

Volume 5 - Number Suppl.1

Article Type: Original Article
Abstract: Objectives: Diabetes is a common metabolic disease with various adverse consequences. Gum olibanum (from trees of the genus Boswellia) has been traditionally used for the treatment of various diseases such as diabetes. The aim of this study was to compare the effects of Gum olibanum powder and placebo on the treatment of type IIdiabetes. Materials and Methods: The inclusion criterion was having diabetes, with a fasting blood sugar (FBS) level of 140-200 mg/dL. This double-blinded clinical trial was conducted on 71 patients with type II diabetes, who were randomly divided into intervention and placebo groups. Patients on standard anti-diabetic therapy (metformin) were treated with Gum olibanum (400 mg capsules) and placebo twice per day for 12 weeks, respectively. FBS, HbA1c, insulin, total cholesterol, low-density lipoprotein (LDL), triglyceride andhigh-density lipoprotein (HDL) were measured. Results: Gum olibanum significantly lowered FBS, HbA1c, insulin, cholesterol, LDL and triglyceride levels (p<0.001, p<0.001, p<0.001, p=0.003, p<0.001 and p<0.001, respectively), without having any significant effects on other serumlipid levels. Liver/kidney function test resultswere not significantly different between the groups at the end of the intervention (p>0.05). Moreover, this plant showed antioxidant properties and no adverse effects. Conclusion: The results suggest that Gum olibanum powder could be used as a safe anti-oxidant, anti-hyperglycemic and antihyperlipidemic agent for type II diabetic patients.