Predictors of bone disease in Egyptian prepubertal children with β-thalassaemia major.

Archives of medical science : AMS

Volume 6 - Number 4

Article Type: ---- Unspecified ----

Thalassaemic osteopathy is a multifactorial disorder and limited information exists about bone accrual and bone mineral density (BMD) in prepubertal thalassaemic children. The study aimed to investigate some potential genetic and biochemical bone markers as possible early predictors of BMD variations in children with β-thalassaemia major (TM) before puberty.