Vaccine-associated paralytic poliomyelitis in a patient with MHC class II deficiency

Journal of Clinical Virology

Volume 2 - Number

Article Type: ---- Unspecified ----
Abstract:

Vaccine-associated paralytic poliomyelitis (VAPP) is a rare complication of oral polio vaccine. We describe a fatal case of VAPP in an 8-month-old boy with Major Histocompatibility Class II deficiency. The isolated poliovirus was a Sabin type 2-type 1 recombinant that showed 1.4% VPI divergence from Sabin type 2. (C) 2007 Elsevier B.V. All rights reserved.