Infliximab in a Patient with Refractory Necrotizing Scleritis Associated with Relapsing Polychondritis

Ocular Immunology and Inflammation

Volume 3 - Number

Article Type: ---- Unspecified ----
Abstract:

Purpose: To describe a case of necrotizing scleritis associated with relapsing polychondritis (RP), which was treated with infliximab. Method: Observational case report. Results: A 60-year-old woman presented with a red eye. She had a past medical history of nose deformity, hearing problem, and tinnitus. Ophthalmological examination disclosed necrotizing scleritis and peripheral ulcerative keratitis. RP was diagnosed. The disease progressed despite treatment with methotrexate and cyclophosphamide, but infliximab resulted in a stabilization of the disease. Conclusion: Infliximab could be a new weapon to treat refractory scleritis due to RP.