High levels of CA125 (over 1,000 IU/ml) in patients with gynecologic disease and no malignant conditions: Three cases and literature review

Archives of Gynecology and Obstetrics

Volume 5 - Number

Article Type: ---- Unspecified ----

Objective: To report the very high serum levels of CA125 in patients with benign gynecologic disease which manifests as pelvic mass. Methods: Clinical data of three cases with high levels of CA125 over 1,000 IU/ml and benign gynecologic conditions were gathered. in Vali-Asr hospital. Results: Three patients were scheduled for laparatomy as ovarian cancer and leiomyosarcoma. Histologic results after laparatomy showed uterine myoma in two patients and endometrioma in a third patient. Conclusion: High levels of CA125 over 1,000 IU/ml, may be showed in other gynecologic conditions with no malignancy. So, other clinical and imaging data could be helpful for differential diagnosis of these patients. © 2007 Springer-Verlag.