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A 24-year-old man presented with papulopustular, rosacea-like centrofacial lesions. Many Demodex mites were found in the affected area by microscopy of smears from pustules. This observation provides further evidence that demodicosis is a condition distinct from common rosacea. Considering clinical similarities of demodicosis, rosacea and some mycotic infections, direct examination to confirm the etiological agent is highly recommended prior to treatment.